Research on Equi Breeze Equine Respiratory Supplement

Equi-Breeze: Research Behind the Formula

Equi-Breeze is built on a foundation of herbal science. Below is a selection of peer-reviewed research supporting the respiratory benefits of the key botanicals used in our formula.

Mullein (Verbascum thapsus)

Anti-inflammatory, antioxidant, and antimicrobial activity
Soothes mucous membranes with mucilage content
Expectorant effect from saponins, supporting mucus clearance
Effective against Klebsiella, Staph, and E. coli in vitro
Antioxidants like vitamin C and flavonoids support lung health

Elecampane (Inula helenium)

Antimicrobial sesquiterpene lactones effective against Staph
Activity against Mycobacterium tuberculosis in vitro
Demonstrated anti-inflammatory properties

Yarrow (Achillea millefolium)

Potential antiviral activity against coronaviruses
Well-established anti-inflammatory effects

Peppermint (Mentha piperita)

Menthol acts as a decongestant to ease breathing
Improves lung function (FVC and peak inspiratory flow)

Malabar Nut (Adhatoda vasica)

Bronchodilator and expectorant effects (vasicine, vasicinone)
Improves lung function and asthma symptoms in clinical trials
Reduces airway inflammation and inflammatory cytokines
Inhibits hypoxia-induced mitochondrial dysfunction
Suppresses mucus overproduction (MUC5AC inhibition)

References

References
African Journal of Respiratory Medicine. (2022). Herbs used in boosting respiratory health.
Amaliyah, E., et al. (2024). The Effectiveness of Peppermint Aromatherapy Inhalation in Nursing Care for Ineffective Airway Clearance in Pulmonary Tuberculosis Patients at Drajat Prawiranegara Hospital, Banten, Indonesia: Case Study. International Journal of Social Science and Economics Research, 2(6), 1562-1577.
Dey, A., et al. (2021). Adhatoda vasica rescues the hypoxia-dependent severe asthma symptoms and mitochondrial dysfunction. American Journal of Physiology-Lung Cellular and Molecular Physiology.
Healthline. (2021). What Is Elecampane Root, and Does It Have Benefits?
Hemmati, A. A., et al. (2011). Yarrow (Achillea millefolium L.) extract impairs the fibrogenic effect of bleomycin in rat lung. Journal of Medicinal Plants Research, 5(10), 1843-1849.
Kahraman, Ç., Ekizoğlu, M., Kart, D., Akdemir, Z. Ş., & Tatlı, İ. İ. (2011). Antimicrobial activity of some Verbascum species growing in Turkey. FABAD Journal of Pharmaceutical Sciences, 36(1), 11-15.
Kumar, K. P. S., et al. (2010). Indian traditional herbs Adhatoda vasica and its Medicinal application. Journal of Chemical and Pharmaceutical Research, 2(1), 240-245.
Longdom Publishing. Vasaka (Adhatoda vasica Nees): Traditional Uses and Medicinal Applications in Ayurveda.
Mahdavi, S., Amiradalat, M., Babashpour, M., Sheikhlooei, H., & Miraj, S. (2015). The antioxidant and antibacterial activities of the essential oil and extracts of Verbascum thapsus L. Journal of Medicinal Plants Research, 9(8), 276-283.
MedicalNewsToday. (2023). Mullein for asthma: What are the benefits?
Memon, T. A., et al. (2023). Inhibition of TRPA1, Endoplasmic Reticulum Stress, Human Airway Epithelial Cell Damage, and Ectopic MUC5AC Expression by Vasaka (Adhatoda vasica; Malabar Nut) Tea. International Journal of Molecular Sciences, 24(12), 10303.
Riaz, M., Zia-Ul-Haq, M., & Jaafar, H. Z. (2013). Common mullein, pharmacological and chemical aspects. Revista Brasileira de Farmacognosia, 23(6), 948-959.
Sánchez-Vioque, R., et al. (2022). Antioxidant, Anti-Inflammatory, and Antibacterial Properties of an Achillea millefolium Extract and Its Supercritical Fractions against Helicobacter pylori. Antioxidants, 11(10), 1960.
Sharma, M., et al. (2022). Evaluating the Potential of Adathoda vasica against Respiratory Diseases: A Comprehensive Review. Current Drug Metabolism.
Speranza, L., Franceschelli, S., Pesce, M., Reale, M., Menghini, L., Vinciguerra, I., ... & Grilli, A. (2010). Antiinflammatory effects in THP-1 cells treated with verbascoside. Phytotherapy Research, 24(9), 1398-1404.
Tatli, I. I., & Akdemir, Z. S. (2006). Traditional uses and biological activities of Verbascum species. FABAD Journal of Pharmaceutical Sciences, 31(2), 85-96.Turker, A. U., & Gurel, E. (2005). Common mullein (Verbascum thapsus L.): recent advances in research. Phytotherapy Research, 19(9), 733-739.